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They might relieve hot flashes, improve sleep, and reduce mood lability by acting on neuroendocrine circuits

The purpose of this review is to (1) detail the renal and cardiovascular mechanisms of incretin-based therapies, (2) summarize the clinical evidence from completed and ongoing CVOTs, (3) discuss emerging agents such as the dual GLP-1/GIP agonist tirzepatide, and (4) highlight remaining knowledge gaps as the therapeutic paradigm shifts from glucose-centric to cardiorenal-centric care

For readers comparing GLP-1 options, our tirzepatide guide may also help you compare treatment paths

Cancer 120 (19), 29802985

The flat pricing is another advantage