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doi: 10.1146/annurev-nutr-061121-084407
C., Marquez-Ruiz, G., Fontecha, J
Still, some early clinical findings hint at potential uses in more specific contexts: Perioperative brain protection: A randomized controlled trial involving 155 liver surgery patients found that ALA reduced oxidative brain injury from anesthesia (sevoflurane) and improved cognitive recovery scores after surgery.31 Neurodegenerative conditions: In a small trial, ALA appeared to slow brain atrophy in patients with secondary progressive multiple sclerosis over a two-year period.32 While promising, this outcome still needs further confirmation
This peptide specifically targets and inhibits the activity of p53, a well-known tumor suppressor protein, allowing for the selective elimination of senescent cells, which are implicated in aging and age-related diseases
