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10.1021/acs.jafc.3c08253 87 WenS.HeL.ZhongZ.ZhaoR.WengS.MiH.et al (2021)

[14] [13] These mechanisms contribute to improved glycaemic control and weight loss, but they can also lead to reduced caloric intake, changes in eating patterns, and occasionally low blood glucose levels (hypoglycaemia), all of which may contribute to feelings of tiredness

With lower estrogen, your body naturally produces more free radicals (unstable molecules that can damage cells) and your mitochondria are a prime target

Of course, you can mix it according to your needs