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In addition to promoting leukocyte adherence and altering endothelial signal transmission and redox-regulated transcription factors, oxidative stress also raises vascular permeability

Glutathione is involved in normal immune function

Glutathione is generally administered in situations where it is deemed necessary during in vitro fertilization (IVF) treatment

The enhanced cellular uptake results in higher intracellular concentrations of glutathione, where it can exert its antioxidant and detoxifying effects more effectively

SSZ was found to suppress the transcription factor AEBP1, thereby down-regulating its direct targets GPX4 and SLC7A11