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versicolor extracts reprogrammed tumor-associated macrophages from M2 to M1 phenotypes, restoring antitumor immune surveillance in TNBC models (Jdrzejewski et al., 2024), while the triterpenoid GA-DM from G

That extra pathway helps tirzepatide produce greater average weight loss in trials, though both are effective once-weekly injections with similar digestive side effects

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