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Fang et al., 2023

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Also, glutamate excitotoxicity NMDA-mediated intra-neuronal calcium overload elevates NO synthesis contributing to oxidative stress particularly the production of reactive nitrogen species which are able to cause defects in DNA and protein phosphorylation pathway (85)

Mercury can also directly accelerate the oxidative destruction of cell membranes and low-density lipoprotein (LDL) cholesterol particles as well as bind to and inactivate the cellular antioxidants N-acetyl cysteine, alpha-lipoic acid, and glutathione

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