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Description

Elimination of Tac metabolites occurs primarily through biliary excretion (more than 95%), while only 0.5% of the parent drug could be found unchanged in the urine or feces (30)

Autonomic dysfunction Autonomic dysfunction in ME/CFS manifests through diverse symptoms, primarily encompassing neurocardiovascular issues like orthostatic intolerance and postural orthostatic tachycardia syndrome (POTS), as well as neurogastrointestinal disturbances [199]