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Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

Results: No differences between treatment groups in behavioral or biologic measures were found

The ANT crystal structures in both cytoplasmic-open (c-state) and matrix-open states (m-state) locked by two inhibitors bound at the solute binding site, carboxyatractyloside and bongkrekic acid respectively, highlighted a conserved alternating-access transport mechanism 5 enabled by the conformational change upon solute binding at the central cavity 6,7

Targeting c-MET in lymphoma Because of its pleiotropic role in oncogenesis and cancer progression, HGF/c-MET is considered to be an important target in anticancer therapy

Each experiment was performed at least three times with cells of a different passage and donor