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Peptides are largely broken down by digestive enzymes in the gastrointestinal tract before they can be absorbed intact, meaning oral peptide supplements typically have very poor bioavailability and may produce little or no physiological effect
MK 677 has also been studied for its ability to counteract diet induced catabolism, to preserve muscle mass during caloric restriction
Although the anti-cancer effects of EGCG may be attributed to a pro-oxidant effect, high oral doses of EGCG (750 1500 mg/kg) have been shown to exert hepatotoxic effects in CF-1 mice
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[DOI] [PubMed] [Google Scholar] 10.Seiwerth S., Rucman R., Turkovic B., Sever M., Klicek R., Radic B., Drmic D., Stupnisek M., Misic M., Vuletic L.B., et al
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