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Serious adverse reactions are rare

Marx N, Federici M, Schtt K, Mller-Wieland D, Ajjan RA, Antunes MJ, et al

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In this context, their potential antitumor relevance is biologically plausible, as they may improve metabolic dysfunction, reduce obesity-related chronic inflammation, and influence nutrient availability and metabolic reprogramming in the TME (66-68)

This hypothesis was further supported by a separate 2020 study, which found that unexplained high serum vitamin B12 levels may be associated with the development of solid cancers, such as breast cancer