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This persistent microglial activation wreaks havoc on neural connectivity and severely impairs neurogenesis, particularly in the hippocampus, the brain's primary memory center

The SURMOUNT trials demonstrated up to 22.5% mean weight loss at the highest dose

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Oral Formulations The only available oral GLP-1 receptor agonist is semaglutide (Rybelsus, Novo Nordisk)

Medical safety risk is low