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It makes constipation harder to resolve, increases the concentration of bile acids that irritate the gut lining, reduces the volume of protective mucus, and impairs the motility that probiotics are trying to support

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It also plays a role in muscle function and the immune system

57,58 A randomized placebo-controlled study in 23 children (aged 58 years) with ADHD as well as iron deficiency (defined by ferritin levels less than 30 ng/mL) showed that 80 mg of ferrous sulfate supplementation daily (providing 16 mg of elemental iron) for 12 weeks resulted in a significant decrease in symptoms

Bromelain protects critically perfused musculocutaneous flap tissue from necrosis