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PMID 24213682

American Journal of Respiratory and Critical Care Medicine, 156 (2)

Mechanistically, GSH depletion does not cause global protein oxidation but instead selectively oxidizes and destabilizes fatty acid synthase while decreasing lipogenic gene expression at the transcriptional level, collectively suppressing lipogenesis

When mitochondria, the organelles in cells that power our bodies, process oxygen, between 1% and 2% gets left behind as free radicals known as reactive oxygen species

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