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While the exact mechanism linking semaglutide to NAION is not fully understood, Kopelman told MNT , there are a few theories. He explained that semaglutide may influence vascular health and blood flow, potentially contributing to ischemic events in predisposed individuals. An ischemic event is when an organ or tissue does not receive adequate blood, and therefore oxygen

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Eli Lilly CEO David Ricks said the company will start large studies "in alcohol abuse and nicotine use, even in drug abuse" The news comes as the body of evidence suggesting that Zepbound and other GLP-1 weight-loss medications could help people with substance use disorders continues to grow