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Implementing these multicellular organoid models in lipedema research will enable high-fidelity analysis of how progenitor and immune cells collectively contribute to the pathological tissue architecture

Submerged cultures on tissue culture plastics are cheap but have a short lifespan and may achieve limited expansion in cell numbers from a tissue sample (Fig

They also act as antioxidants, supporting overall health and aiding in the absorption of iron

Key Takeaway: Vitamin C acts as a biological recharger for glutathione

We performed meta-regression to determine the association of treatment outcomes with patient characteristics and study design factors if significant heterogeneity was identified