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Abstract This study analyzed adverse events (AEs) of GLP-1RA and metformin combination therapy using FAERS data (20042024)

Clinical manifestations include acute pain crises, hemolytic anemia, and multi-organ dysfunction, imposing substantial morbidity and mortality challenges

Compounding pharmacies : Some offer custom combos, but FDA warns against this due to contamination risks, inconsistent dosing, and lack of safety data (no large trials)

Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells

Three models were constructed: Model 1 (crude model), Model 2 (adjusted for age and sex), and Model 3 (fully adjusted for potential confounders including BMI, blood pressure, lipid profile, renal function, osteocalcin (OCN), vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status)