Well, I started at the lowest dose and took that for 4 weeks before moving to the next dose, which I believe was 0.5 mg
References & Sources SURPASS-2 Trial (N Engl J Med) SURMOUNT-1 Trial (N Engl J Med) SELECT Trial Semaglutide CV Outcomes (N Engl J Med) SUMMIT Trial Tirzepatide HFpEF (N Engl J Med) Eli Lilly SURPASS-2 Results (Press Release) Eli Lilly SURMOUNT-1 Results (Press Release) ADA SURPASS Data Presentation SUMMIT Trial ACC Summary SELECT Trial ACC Summary Disclaimer: This information is intended for general knowledge and informational purposes only and does not constitute medical advice
Jon writes evidence-led guidance on medicines, supplements and nutrient interactions, helping readers make informed choices without relying on exaggerated health claims
When beta-catenin accumulates in the nucleus of dermal papilla cells (the "command center" at the base of each follicle), it activates transcription factors (LEF-1, TCF-1, TCF-3, TCF-4) that upregulate genes like c-Myc and cyclin D1
Nutrients 15 , 4601 (2023)