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doi: 10.1038/s41593-021-00975-6 390 XieX.MaG.LiX.ZhaoJ.ZhaoZ.ZengJ.et al

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Bioavailability of the subcutaneous formulation is approximately 89%, ensuring consistent drug exposure across patients

Estimated free copper = total serum copper estimated ceruloplasmin-bound copper This is also called estimated non-ceruloplasmin-bound copper

Combination therapies, integrating RAAS modulators, GLP-1 agonists, SGLT-2 inhibitors, holding promise for synergistic effects, could exert their potential specific protective ability unless the underlying mechanism and setbacks could be thoroughly comprehended