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Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1

In addition, other studies demonstrated the benefit of D-2 stimulation in patients with negative symptoms of schizophrenia (97, 98)

Excessive NO competes with the antioxidants, MnSOD and GSH, for superoxide and promotes the generation of peroxynitrite

Oxidative stress is the disturbance in the balance between the generation of free radicals, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), and antioxidant defenses, and can cause oxidative damage to diverse cellular components, such as membranes, proteins, and DNA

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