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The regulation of SELENOP synthesis seems to be even more sophisticated than that for other selenoproteins, due to the necessity to incorporate multiple Sec elements (Shetty and Copeland, 2018b)

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Isothiocyanates can react with sulfhydryl residues of Keap1, causing the release of Nrf2

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The transport system consists of three main proteins, the first of which is the enzyme carnitine palmitoyltransferase I (CPTI) present in the mitochondrial outer membrane that complexes with a long-chain acyl-CoA synthetase and the voltage-dependent anion channel, while the second transport component is carnitine:acylcarnitine translocase (CACT), an integral inner membrane protein, which complexes with carnitine palmitoyltransferase II (CPTII) located on the matrix side of the inner membrane