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Unlike sterile water for injection, which is intended for single-use only and must be discarded after the seal is broken, bacteriostatic water can be safely used multiple times over a period of up to 28 days after initial puncture

West MB, Wickham S, Quinalty LM, Pavlovicz RE, Li C, Hanigan MH

The effects look a lot like what regular aerobic exercise does metabolically, which is where the nickname comes from

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Dose escalation phase (titration) Tirzepatide titration (dose escalation) typically follows this schedule: Month 2: 4-6 mg once weekly Month 3: 6-8 mg once weekly Month 4: If tolerated, increase to 8-10 mg once weekly Month 5: If the dosage needs to be escalated further, increase to 10-12 mg once weekly Month 6 and onward: If the dosage needs to be escalated further, increase to 12-14 mg once weekly The maximum dosage is typically 14 mg once weekly if further glycemic control or weight loss is required