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Insulin resistance and glucose metabolism disorders are not only associated with metabolic diseases like diabetes but also closely linked to the onset and progression of neurodegenerative diseases

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7 As a combination product, phentermine with topiramate is approved for weight management in children aged 12 years and older with BMI 95th percentile or BMI 27 kg/m 2 and 1 weight-associated comorbidity, in addition to lifestyle modifications

Phase 1 of Clinical Trials : Objective: To assess the safety, tolerability, and initial efficacy of the drug

Overall health status: Diabetes impairs healing through vascular damage, impaired immune function, advanced glycation end products