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Moreover, GHS-R1a is often referred to as the ghrelin receptors because ghrelin seems to be its primary natural ligand

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(4) Heike Stier, Evert Vos, David Kenley (2013) Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans Journal of Endocrinology and Metabolism, 2013, Volume 3 (Issue 1-2), Pages 7-15

Many patients who experience appetite return benefit from stepping up to higher weekly doses, restoring the initial appetite-suppressing effect they experienced at 12 weeks of treatment