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Furthermore, the literature indicates that aside from their benefits in weight management and glycemic control, GLP-1 RAs have favorable effects on metabolic profiles, including blood pressure and lipid levels 22

Semaglutide (Wegovy, Ozempic) received FDA approval for chronic weight management in 2021, followed by tirzepatide (Zepbound) in 2023, both demonstrating substantial weight loss in clinical trials

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For participants without diabetes at baseline, the research demonstrated preventive effects on glucose metabolism