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Typical dosing for Trulicity starts at 0.75 mg once a week and then increases to 1.5 mg, 3 mg or 4.5 mg as recommended by a healthcare provider

Individuals with certain health conditions, such as Lebers disease (a rare inherited eye disease), should avoid B12 supplements as it can worsen the condition

It is not recommended for pregnant or breastfeeding women, or for those with certain thyroid conditions, such as medullary thyroid carcinoma, or a personal or family history of thyroid cancer

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As noted in the Wegovy SmPC, severe gastrointestinal adverse reactions may lead to dehydration with potential risk of acute kidney injury