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STEP-1 took 1961 adults with a BMI 30 (or 27 in people with 1 weight-related coexisting condition) without T2D and demonstrated mean weight reduction of 14.8% in participants taking semaglutide 2.4 mg weekly (vs
When you add 2mL bacteriostatic water, the final volume is approximately 2mL, not 2.1mL or 3mL
The novel use of the internal reference, LR3, spiked into the analytical samples allows for the entire workflow of the assay, sample preparation to LC-MS/MS detection, to be monitored and provides quality assurance of the assay performance
Lower starting doses also help distinguish peptide effects from coincidental events
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