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The combination therapy decreases ENaC expression in association with the increase in USE in patients with DKD, and therefore add-on therapy with DPP4is to SGLT2is might become a potent therapeutic combination to attenuate salt sensitive hypertension and ameliorate kidney damage

Sodium borohydride (NaBH 4 ), silver nitrate (AgNO 3 ), l-ascorbic acid, and cetyltrimethyl ammonium bromide (CTAB) were provided by Sinopharm Chemical Reagent Company (Beijing, China)

This is why it is a good idea to talk with a healthcare provider