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The central leptin gene therapy has also been effective to insulin-deficient diabetes in obesity animal models such as ob/ob mise, diet-induced obese mice, and insulin-deficient type 1 diabetes mice (Kojima et al., 2009), and in patients with inactivating mutations in the leptin gene (Farooqi et al., Herein, we review the role of leptin in regulating feeding behavior and glucose metabolism and also the therapeutic potential of leptin in obesity and diabetes mellitus

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Came to my hotel room, treated me and 4 other of my friends

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