should i switch to tirzepatide from semaglutide Switching Between and Tirzepatide: Efficacy, Dosing Protocols, and What Expect Switching from Semaglutide to Tirzepatide:

For those who want to understand this transition in the context of other compounds, the guide on conversion between GLP-1 compounds provides useful reference points for dose equivalency thinking

Its circulating half-life is relatively short

The presence of a local nasal condition, such as inflammation or congestion, can interfere with the absorption and distribution of the medication throughout the body

Curious the Navitus as a PBM is publishing this considering that it maintains exclusionary formularies which exclude generic versions of the GLP-1 Victoza or Saxenda (liraglutide) from Teva and Biocon (with more now pending regulatory approval decisions) from its formularies, raising questions as to how much influence PBM formulary managers have in driving formulary decisions when confronted by an employer plan sponsor demanding rebate pass-thru

switching between them does not prevent it and introduces more risks than benefits