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There are many reasons to try and optimize growth hormone and IGF-1 levels as we age, including helping to sustain lean muscle mass while preventing belly fat, maintaining healthy bone mineral density, and supporting heart and brain health

Notably, DIO rats receiving 0.3 mol/kg of drug lost around 13 g of body weight in 14 days

However, weight loss may change your levothyroxine requirements, so your provider should monitor your TSH every 612 months during active treatment

If plateaus extend beyond 6 to 8 weeks despite optimized lifestyle factors, discuss dose escalation with your prescriber

(d) Mounjaro, containing tirzepatide