The STEP UP trial data provides the foundation for this approval
Studies of -carbolines in coffees are confounded significantly due to the common issues of studying coffee (cultivar, soil and inputs, growing conditions, processing methods, drying methods, storage time, roast level, etc.), but seem to have even wider swings of results than other compounds
Most of the HTN-I patients had a combination treatment (ACE inhibitor + statin), which has been reported to have antioxidant effects (Profumo et al., 2014)
Goal: Maximize sperm production while on testosterone therapy Approach: HCG 500 IU subcutaneously every other day Consider adding FSH or HMG if response insufficient after 3 months Semen analysis at baseline, 3 months, and 6 months Timeline: Initial testosterone response: 2-4 weeks Sperm appearance: 3-4 months Significant count improvement: 4-6 months If conception remains the urgent priority, discontinuing TRT while increasing HCG to 3000 IU every other day accelerates recovery
Barbara Geisser Barbara S
