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Yes, skipping meals can sometimes lead to weight gain over time

Individuals who are overweight or obese (with a BMI of 25 or higher) or have one or more obesity-related conditions may be suitable candidates for GLP-1 therapy

One documented case involved a 38-year-old male on TRT and MK-677 who added 10mg daily of injectable 5-amino-1MQ

The mechanism for bronchospasm remains speculative but may involve NO-mediated bronchiolar smooth-muscle relaxation tipping into paradoxical constriction in susceptible individuals