Source: (1) World Obesity Atlas 2023
This not only indicates that oral semaglutide has similar efficacy in the treatment of obesity compared to the injectable form but also that its oral route of administration may help overcome psychological barriers to injection therapy for some patients, thus improving compliance and acceptance
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The protective cardiovascular effects of GLP-1RAs can be through improving glycemic control, as reducing HbA1c can improve blood pressure, body weight, hyperlipoproteinemia, and inflammation