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Written by Rachel Kim, MS, RD , Registered Dietitian & Health Writer Medically reviewed by FormBlends Clinical Review , Clinical Pharmacist & Medical Reviewer Published: Key Takeaway Compare semaglutide vs Contrave for weight loss

Clinical trials of Ozempic (semaglutide) have shown average A1C reductions of about 1.5% to 2.0%, while Mounjaro (tirzepatide) has demonstrated reductions of up to 2.4% in some studies

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Serious Adverse Events Insulin Resistance: Increasing growth hormone can sometimes cause blood sugar levels to rise