melanotic macule nail The Art of Findings in Patients with Skin of Color Figure 3 from Clinicopathologic features

However, during periods of physical stress, illness, or intense training, it becomes conditionally essential, meaning your body's demand exceeds its natural production capacity

Nat Commun (2014) 5:4497

B Vitamins (especially B6, B12, and folate): Support the methylation cycle, which plays a key role in detox and glutathione recycling

However, you need to be aware of potential side effects if you take large doses of either one of these substances.

Antioxidant Protection If youve ever made a fruit salad, you likely know the chefs trick to sprinkling a little lemon or lime juice over the fruit to keep it from turning brown