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1 Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 2 Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy, 3 Department of Developmental Neuroscience, IRCCS, Stella Maris Foundation, Pisa, Italy, 4 Interdisciplinary Research Center Health Science, SantAnna School of Advanced Studies, Pisa, Italy

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Out of those participants, 85% lost at least 5% of their weight (versus 26% with placebo), 69% lost at least 10% (vs 12%), 54% lost at least 15% (vs 6%), and 34% lost at least 20% (vs 3%)