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GLP-1 suppresses appetite in the brains hunger center (hypothalamus)

Gather Supplies Essential items : Before you begin, ensure you have the following: Your GLP-1 medication pen (or vial and insulin injection needles in the case of compounded medication) Alcohol swabs for skin disinfection

generally compatible with fluoxetine but requires medical supervision Liraglutide (Saxenda) and semaglutide (Wegovy): GLP-1 receptor agonists with no known direct pharmacokinetic interactions with SSRIs according to their SmPCs, though they can cause gastrointestinal side effects requiring monitoring [8] Naltrexonebupropion (Mysimba): requires particular caution due to fluoxetine's effect on bupropion metabolism and associated seizure and neuropsychiatric risks Your GP will assess whether you meet NICE criteria for these medicines (typically a BMI 30 kg/m, or 27 kg/m with weight-related comorbidities) and whether they are appropriate alongside your fluoxetine treatment

Also see creatine and GLP-1 for information on supplements that support muscle preservation