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Cardiometabolic improvements across published trials include reductions in blood pressure, triglycerides, LDL-cholesterol, HbA1c, and fasting glucose

DPP4 can cleave various peptides, leading to inactivation and/or generation of new bioactive peptides

August 2025 : The US FDA approved Wegovy (semaglutide 2.4 mg) for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis), in combination with a reduced-calorie diet and increased physical activity

Proper storage: Keep patches in a cool, dry place away from direct sunlight to preserve their integrity