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If those sensations gradually become less noticeable, some may incorrectly assume the medication is no longer effective. "Our results suggest that patients may experience a partial return of appetite sensations over time, without losing the medication's benefit of continuing to reduce calorie intake, which is needed to maintain their new, lower body weight," Tronieri said

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If your blood glucose readings start creeping up on the same dose and diet, expired or degraded medication should be on your list of potential causes

Physical activity is a key component of weight loss

Those factors should be compared on the same basis