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A critical emphasis is placed on continuous monitoring for adverse effects and ensuring the long-term efficacy and safety of these agents in the pediatric population, with the ultimate goal of defining optimal treatment regimens and identifying patient populations that derive maximal benefit

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Many describe the experience as feeling like walking directly on bone

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In short, the cells were incubated with 700 L culture medium including the core-H 1 H 2 H 3 probes (50 mg/ml) for 4 h, then were washed three times with hybridization buffer (pH 7.4)