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Seong JM, Yee J, Gwak HS

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Through continuously improving understanding of the pathway, phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was found to neutralize the activity of PI3K by dephosphorylating the downstream products of PI3K, which include ephosphatidylinositol-3,4-bisphosphate (PIP2) and phosphatidylinositol -3,4,5-triphosphate (PIP3) [14, 26]

So you might eat the exact same way you did at 25, but your bodys not processing it the same anymore