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This increased vascular permeability promotes massive leukocyte migration across the endothelium and protein leakage into the alveolar lumen, ultimately causing pulmonary oedema

Holsts great scientific achievements include the discovery of GLP-1 (glucagon-like peptide 1) a gut hormone regulating insulin secretion and appetite and food intake and his subsequent both basic and translational research in this field

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Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis