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Patients with a history of heart disease, stroke, or unstable cardiac conditions should discuss tirzepatide with their cardiologist and primary care provider

The medication also serves to slow down gastric emptying, meaning that food stays in the stomach for longer before being digested

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However, some people experience a temporary "detox" period as the body processes accumulated toxins

By flagging potential mismatches between guideline-based eligibility and actual prescription patterns, such systems may help to reduce inequities and align therapeutic decisions with evidence-based priorities