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PMID: 12209581

Has a Designated Federal Official (DFO)

Furthermore, phosphorylated JNK induces oxidative stress, mitochondrial membrane permeability, and dysfunction through the activation of Bax, the translocation of Bax to the mitochondria, the opening of the mitochondrial permeability transition pore, and Src-dependent inhibition of the electron transport complex

The copper part is essential to the molecules function, as it carries copper and hands it off where cells can use it

The absence of serious adverse events in short-term trials does not establish long-term safety, particularly given the compound's prolonged use in underground communities