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Transcriptomics in peripheral tissues Bulk RNA sequencing showed that GLP-1GIPLani robustly induced anti-inflammatory gene programmes in the liver and skeletal muscle (Fig
Nevertheless, in vitro studies on blood vessels have shown that GLP-1RAs inhibit vascular smooth muscle cell proliferation, reduce reactive oxygen species, and increase nitric oxide in vascular endothelial cells [37]
The LBPs, FMT, pre/probiotics, postbiotics, synbiotics, and dietary interventions have the potential for disease prevention or treatment by modulating gut microbiota
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