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Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis

Nicotinamide adenine dinucleotide, or NAD+, is the active form of niacin, vitamin B3

Newer ones such as semaglutide and tirzepatide, broadly known as GLP-1s, have exploded in popularity for weight loss and have shown promise for treating other conditions, such as addictions and neurodegenerative and liver diseases

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While semaglutide remains the cornerstone of GLP-1-based weight management , cagrilintide introduces a new dimension by activating amylin receptors