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This not only serves as additional energetic resource, but also generates a number of biologically active molecules such as diacylglycerol, cholesterol, ceramide, sphingosine, PIP2, IP3 which are involved in the activation of a variety of signaling pathways associated with cancer progression, metastases and therapy resistance e.g

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The proposed mechanism involves improved blood flow to exercising muscle through enhanced nitric oxide production, reduced oxidative damage via antioxidant effects, and more efficient substrate utilization during recovery [3]

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Detailed statistics are in Supplementary Table 1