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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

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Their structural resemblance to biological membranescomprising phospholipids and cholesterol, confers enhanced biocompatibility and facilitates efficient transfollicular drug delivery [213, 214]

Comment Apoptosis is a form of genetically controlled programmed cell death. Microscopically in H&E-stained tissue sections, apoptosis appears as dense eosinophilic shrunken cell bodies with maintenance of membrane integrity, nuclear fragmentation and cytoplasmic budding, and without an inflammatory response