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During my residency, I encountered a patient who had been taking what he called his daily vitamin D megadose 50,000 IU every day for six months after reading online that more is better. He came to the emergency department with kidney stones and severe fatigue

doi:10.1016/j.chemosphere.2020.127238

Direct comparison meta-analysis When researchers pooled data from comparable studies, retatrutide produced an average of 16.34 kg of weight loss compared to 11.82 kg for tirzepatide

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