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Such a trial would likely take several years and cost tens of millions of dollars, but the potential payoff, a new treatment option for a condition that affects over a billion people worldwide, justifies the investment

Maintaining proper fluid balance and moist respiratory tissues is critical for optimal respiratory functioning, immune surveillance, and oxygen exchange

Wanting data on what happens after discontinuation is just as important as the initial results

The efflux liability for both compoundseach being a P-glycoprotein substrate (Table 4)suggests that co-administration with efflux inhibitors might enhance systemic exposure, an approach under active investigation for overcoming chemotherapy resistance 69

Phototherapy is also used, however long-term harmful effects include premature skin aging, hyperpigmentation, and increased risk for skin cancer [22]